With the nationalist composer Richard Wagner as Friedrich Nietzsche’s surrogate father and the Nazis’ appropriation of Wagner’s music and Nietzsche’s philosophy, many have questioned whether Nietzsche and his works are on the right side of history. Seeking Nietzsche ponders who determines the answer to this question. When Nietzsche falls into madness, his nationalist sister, Elisabeth, takes over the management of his literary estate, but knowing that the siblings disagree on just about everything, Nietzsche’s friend, Lou Salomé, takes it upon herself to recover Nietzsche’s legacy and reveal his inner psychology. Meanwhile, Elisabeth outlives Nietzsche by thirty-five years and becomes close to Hitler. Influenced by Nietzsche’s theory of eternal recurrence, as well as his madness at the end of his life, the narrative jumps back and forth in time and into the afterlife to tell the tale of the ever-suffering philosopher.